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1

Silicon chip-based patch-clamp electrodes integrated with PDMS microfluidics

Rigo Pantoja, John M. Nagarah, Dorine M. Starace, Nicholas A. Melosh, Rikard Blunck, Francisco Bezanilla, James R. Heath

Journal:

Biosensors and Bioelectronics

Year:

2004

Language:

english

File:

PDF, 301 KB

english, 2004

2

Gating charge displacement in voltage-gated ion channels involves limited transmembrane movement

Chanda, Baron, Kwame Asamoah, Osei, Blunck, Rikard, Roux, Benoît, Bezanilla, Francisco

Journal:

Year:

2005

Language:

english

File:

PDF, 466 KB

english, 2005

3

A hybrid approach to measuring electrical activity in genetically specified neurons

Chanda, Baron, Blunck, Rikard, Faria, Leonardo C, Schweizer, Felix E, Mody, Istvan, Bezanilla, Francisco

Journal:

Nature Neuroscience

Year:

2005

Language:

english

File:

PDF, 522 KB

english, 2005

4

Bilayer Reconstitution of Voltage-Dependent Ion Channels using a Microfabricated Silicon Chip

Pantoja, Rigo, Sigg, Daniel, Blunck, Rikard, Bezanilla, Francisco, Heath, James R.

Journal:

Biophysical Journal

Year:

2001

Language:

english

File:

PDF, 220 KB

english, 2001

5

Determining The Coupling Between Subunits In Kcsa Using Single Channel Fluorescence Spectroscopy

McGuire, Hugo, Bezanilla, Francisco, Blunck, Rikard

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 37 KB

english, 2009

6

Movement of the S4-S5 Linker of KvAP during Gating

Faure, Elise, McGuire, Hugo, Marsolais, Mireille, Blunck, Rikard

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 39 KB

english, 2012

7

An Automated Method to Study Oligomerization of Single Membrane-Bound Proteins using Fluorescence Imaging

McGuire, Hugo, Aurousseau, Mark, Bowie, Derek, Blunck, Rikard

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 53 KB

english, 2012

8

Detecting Rearrangements of Shaker and NaChBac in Real-Time with Fluorescence Spectroscopy in Patch-Clamped Mammalian Cells

Blunck, Rikard, Starace, Dorine M., Correa, Ana M., Bezanilla, Francisco

Journal:

Biophysical Journal

Year:

2004

Language:

english

File:

PDF, 544 KB

english, 2004

9

Black Lipid Membranes: Visualizing the Structure, Dynamics, and Substrate Dependence of Membranes

Ries, Ryan S., Choi, Hyeon, Blunck, Rikard, Bezanilla, Francisco, Heath, James R.

Journal:

Journal of Physical Chemistry B

Year:

2004

Language:

english

File:

PDF, 546 KB

english, 2004

10

Occupancy of a Single Binding Site is Sufficient for AMPAR Activation

Bhattacharyya, Indrani, Blunck, Rikard

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 41 KB

english, 2014

11

A Molecular Mechanics Model of a Closed Voltage-Gated Potassium Channel Generated from S4-S5 Linker LRET Measurements

Starek, Greg, Faure, Élise, McGuire, Hugo, Blunck, Rikard, Bernèche, Simon

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 39 KB

english, 2013

12

Single Molecule Fluorescence Study of the B. Thuringiensis Toxin Cry1Aa Reveals Tetramerization

McGuire, Hugo, Groulx, Nicolas, Laprade, Raynald, Schwartz, Jean-Louis, Blunck, Rikard

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 43 KB

english, 2012

13

FRET Quenching by a Hybrid Voltage Sensor (Hvos) Reveals that the Na/Glucose Cotransporter (SGLT1) Is a Disulfide-Bridged Homodimer with Re-Entrant 12-13 Loop

Sasseville, Louis J., Coady, Michael J., Blunck, Rikard, Lapointe, Jean-Yves

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 40 KB

english, 2013

14

Lipid Affinity to the Voltage-Gated Potassium Channel KvAP

Faure, Elise, Thompson, Christine, Blunck, Rikard

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 58 KB

english, 2014

15

Mode Shift of the Voltage Sensors in Shaker K+ Channels is Caused by Energetic Coupling to the Pore Domain

Haddad, Georges A., Blunck, Rikard

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 36 KB

english, 2011

16

Gating and Stoichiometry of Heteromeric Kainate Receptors

Brown, Patricia, Aurousseau, Mark, McGuire, Hugo, Blunck, Rikard, Bowie, Derek

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 38 KB

english, 2012

17

Investigating the Electromechanical Coupling in voltage-gated K+ channels

Batulan, Zarah, Haddad, Georges A., Marsolais, Mireille, Blunck, Rikard

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 39 KB

english, 2009

18

Towards Simultaneous Single Channel Current and Fluorescence Recordings in Planar Lipid Bilayer

McGuire, Hugo, Blunck, Rikard

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 56 KB

english, 2010

19

Influence of Lipid Bilayer Thickness on Ion Channels Using Single-Channel Voltage-Clamp Fluorescence Imaging

McGuire, Hugo, Blunck, Rikard

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 68 KB

english, 2014

20

Molecular Determinants of the Slow Off-Gating Component in Shaker K+ Channels

Batulan, Zarah, Haddad, Georges A., Blunck, Rikard

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 58 KB

english, 2010

21

Cytosolic Activation Dynamics in the KV Channel Probed by a Fluorescent Unnatural Amino Acid

Kalstrup, Tanja, Blunck, Rikard

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 63 KB

english, 2014

22

Rapid Topology Determination of Membrane Proteins: Pore-Forming Mechanism of Bt toxin Cry1Aa

Groulx, Nicolas, Juteau, Marc, Schwartz, Jean-Louis, Laprade, Raynald, Blunck, Rikard

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 38 KB

english, 2009

23

Do Lipids Show State-dependent Affinity to the Voltage-gated Potassium Channel KvAP?

Faure, Élise, Thompson, Christine, Blunck, Rikard

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.68 MB

english, 2014

24

Role of the Voltage Sensing Domain S1-S4 in TRPV1 Channels

Zhao, Juan, Blunck, Rikard

Journal:

Biophysical Journal

Year:

2015

Language:

english

File:

PDF, 41 KB

english, 2015

25

A Point Mutation Causing Episodic Ataxia Reveals Functional Link between Voltage Sensor and Selectivity Filter in Shaker Kv Channels

Petitjean, Dimitri, Blunck, Rikard

Journal:

Biophysical Journal

Year:

2015

Language:

english

File:

PDF, 47 KB

english, 2015

26

Studying Clustering of KcsA Channels using Single-Channel Voltage-Clamp Fluorescence Imaging

McGuire, Hugo, Blunck, Rikard

Journal:

Biophysical Journal

Year:

2015

Language:

english

File:

PDF, 43 KB

english, 2015

27

Probing the S4-S5 Linker Movement During Activation in KV Channels

Kalstrup, Tanja, Blunck, Rikard

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 39 KB

english, 2016

28

Non-Canonical Start Codons Reinitiate Translation in N-Terminal Truncated Kv Channels

Kalstrup, Tanja, Blunck, Rikard

Journal:

Biophysical Journal

Year:

2015

Language:

english

File:

PDF, 42 KB

english, 2015

29

Structure of anthrax lethal toxin prepore complex suggests a pathway for efficient cell entry

Fabre, Lucien, Santelli, Eugenio, Mountassif, Driss, Donoghue, Annemarie, Biswas, Aviroop, Blunck, Rikard, Hanein, Dorit, Volkmann, Niels, Liddington, Robert, Rouiller, Isabelle

Journal:

The Journal of General Physiology

Year:

2016

Language:

english

File:

PDF, 2.46 MB

english, 2016

30

Molecular Interactions between Kv4.3 and DPP6 - The Biochemical Anatomy of Idiopathic Ventricular Fibrillation

Sharmin, Nazlee, Mohler, Peter, Blunck, Rikard, Nattel, Stanley

Journal:

Biophysical Journal

Year:

2017

Language:

english

File:

PDF, 49 KB

english, 2017

31

Stoichiometries of HCN-KCNE2 Channel

Lussier, Yoann, Möller, Lena, Fürst, Oliver, Blunck, Rikard, D'Avanzo, Nazzareno

Journal:

Biophysical Journal

Year:

2017

Language:

english

File:

PDF, 48 KB

english, 2017

32

The Isolated Voltage Sensing Domain of the Shaker Potassium Channel forms a Cation Channel

Zhao, Juan, Blunck, Rikard

Journal:

Biophysical Journal

Year:

2017

Language:

english

File:

PDF, 46 KB

english, 2017

33

Probing the Movement of the Ball and Chain during N-type Inactivation in Kv Channels

Kalstrup, Tanja, Pandey, Roshan, Blunck, Rikard

Journal:

Biophysical Journal

Year:

2017

Language:

english

File:

PDF, 43 KB

english, 2017

34

Full-length Cellular Beta-secretase Has a Trimeric Subunit Stoichiometry, and Its Sulfur-rich Transmembrane Interaction Site Modulates Cytosolic Copper Compartmentalization

Liebsch, Filip, Aurousseau, Mark R. P., Bethge, Tobias, McGuire, Hugo, Scolari, Silvia, Herrmann, Andreas, Blunck, Rikard, Bowie, Derek, Multhaup, Gerd

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 3.41 MB

english, 2017

35

Voltage-clamp Fluorometry in Xenopus Oocytes Using Fluorescent Unnatural Amino Acids

Kalstrup, Tanja, Blunck, Rikard

Journal:

Journal of Visualized Experiments

Year:

2017

Language:

english

File:

PDF, 943 KB

english, 2017

36

Reinitiation at non-canonical start codons leads to leak expression when incorporating unnatural amino acids

Kalstrup, Tanja, Blunck, Rikard

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 1.17 MB

english, 2015

37

The Human Sodium-Glucose Cotransporter (hSGLT1) Is a Disulfide-Bridged Homodimer with a Re-Entrant C-Terminal Loop

Sasseville, Louis J., Morin, Michael, Coady, Michael J., Blunck, Rikard, Lapointe, Jean-Yves, van der Goot, F. Gisou

Journal:

Year:

2016

Language:

english

File:

PDF, 1.13 MB

english, 2016

38

S4–S5 linker movement during activation and inactivation in voltage-gated K + channels

Kalstrup, Tanja, Blunck, Rikard

Journal:

Proceedings of the National Academy of Sciences

Year:

2018

Language:

english

File:

PDF, 1.96 MB

english, 2018

39

Mechanism of Electromechanical Coupling in Voltage-Gated Potassium Channels

Blunck, Rikard, Batulan, Zarah

Journal:

Frontiers in Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.89 MB

english, 2012

40

Single Channel Studies of the Cation Permeation Pathway of the Shaker Kv Isolated Voltage-Sensing Domain (iVSD)

Zhao, Juan, Blunck, Rikard

Journal:

Biophysical Journal

Year:

2019

Language:

english

File:

PDF, 44 KB

english, 2019

41

Single Channel Studies of the Cation Permeation Pathway of the Shaker Kv Isolated Voltage-Sensing Domain (iVSD)

Zhao, Juan, Blunck, Rikard

Journal:

Biophysical Journal

Year:

2019

File:

PDF, 44 KB

2019

42

Disease-linked mutations alter the stoichiometries of HCN-KCNE2 complexes

Lussier, Yoann, Fürst, Oliver, Fortea, Eva, Leclerc, Marc, Priolo, Dimitri, Moeller, Lena, Bichet, Daniel G., Blunck, Rikard, D’Avanzo, Nazzareno

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 4.20 MB

english, 2019

43

Molecular Interactions that Contribute to the Regulation of HCN Channels by KCNE2

Lussier, Yoann, Callahan, Karen, Blunck, Rikard, D'Avanzo, Nazzareno

Journal:

Biophysical Journal

Year:

2018

File:

PDF, 39 KB

2018

44

Mode Shift of Shaker Isolated-Voltage Sensing Domain

Zhao, Juan, Blunck, Rikard

Journal:

Biophysical Journal

Year:

2018

File:

PDF, 43 KB

2018

45

Determining the correct stoichiometry of Kv2.1/Kv6.4 heterotetramers, functional in multiple stoichiometrical configurations

MÃ¶ller, Lena, Regnier, Glenn, Labro, Alain J., Blunck, Rikard, Snyders, Dirk J.

Journal:

Proceedings of the National Academy of Sciences

Year:

2020

File:

PDF, 2.01 MB

2020

46

Choosing the Correct Stoichiometry from Single Subunit Counting Data

Moeller, Lena, Labro, Alain J., Snyders, Dirk J., Blunck, Rikard

Journal:

Biophysical Journal

Year:

2020

File:

PDF, 43 KB

2020

47

Position of Inactivation Particle of Shaker Kv Channels in Resting State

Pandey, Roshan, Kalstrup, Tanja U., Blunck, Rikard

Journal:

Biophysical Journal

Year:

2020

File:

PDF, 45 KB

2020

48

Reply to Pisupati et al.: Evaluating single subunit counting data to find the correct stoichiometry

MÃ¶ller, Lena, Regnier, Glenn, Labro, Alain J., Snyders, Dirk J., Blunck, Rikard

Journal:

Proceedings of the National Academy of Sciences

Year:

2020

File:

PDF, 488 KB

2020

49

A Common Kinetic Property of Mutations Linked to Episodic Ataxia Type 1 Studied in the Shaker Kv Channel

Zhao, Juan, Petitjean, Dimitri, Haddad, Georges A., Batulan, Zarah, Blunck, Rikard

Journal:

International Journal of Molecular Sciences

Year:

2020

File:

PDF, 1.86 MB

2020

50

A Variant in the Nicotinic Acetylcholine Receptor Alpha 3 Subunit Gene Is Associated With Hypertension Risks in Hypogonadic Patients

Wu, Tao, Wang, Yujia, Shi, Wei, Zhang, Bi-Qi, Raelson, John, Yao, Yu-Mei, Wu, Huan-Dong, Xu, Zao-Xian, Marois-Blanchet, Francois-Christophe, Ledoux, Jonathan, Blunck, Rikard, Sheng, Jian-Zhong, Hu, Sh

Journal:

Frontiers in Genetics

Year:

2020

File:

PDF, 2.23 MB

2020